Total Lyme Testing

Solutions for STTT and MTTT

Gold Standard Diagnostics is the only company offering kits in the U.S. to fulfill Lyme testing requirements for both the Standard and Modified two-tiered testing algorithms. Our four EIA kits and two lmmunoblot kits allow flexibility for your lab to meet your clients’ needs. AII products are FDA cleared, and testing can be fully automated on open processing platforms.

  • EIA & Blot Lyme assays available for Standard and Modified Algorithms
  • Gold Standard Diagnostics Borrelia burgdorferi VlsE-OspC IgG/IgM ELISA Test Kit is key to both methods
  • Maximize lab efficiency with the right approach for early detection
  • FDA cleared

Gold standard diagnostics borrelia burgdorferi VisE-OspC igG/igM Elisa test kit 

Gold Standard Diagnostics’ Borrelia burgdorferi VlsE-OspC lgG/IgM ELISA Test Kit includes recombinant VlsE and OspC antigens to achieve sensitivity comparable to a standard first tier screening assay and specificity comparable to an immunoblot.

The B. burgdorferi VlsE-OspC lgG/lgM EIA assay uses the GSD Standard Lyme EIA protocol with a 15/15/15 incubation.

The Modified Two-Tiered Testing algorithm (MTTT) for Lyme Disease diagnosis is based on two EIA tests. This is an alternate option to the Standard Two-Tiered Testing algorithm (STTT) in which a positive screen result is confirmed with an immunoblot.

Using the Borrelia burgdorferi VlsE-OspC lgG/lgM ELISA Test Kit as the first tier in combination with a second GSD Lyme EIA as the second tier in the MTTT algorithm, we maintain > 98% specificity while demonstrating a nearly 20% increase in Early Lyme Disease detection compared to the STTT.

 

 

Recombinant Antigen Assay: Borrelia burgdorferi IgG/IgM VIsE-OspC ELISA Test Kit

Includes the recombinant antigens VIsE and OspC to achieve excellent sensitivity and specificity.

GSD Whole-Cell Sonicate ELISA Kits: Borrelia burgdorferi IgG/IgM, Borrelia Burgdorferi IgG, Borrelia burgdorferi IgM ELISA Test Kits

  • SUPERIOR SENSITIVITY - Includes antigens from B. burgdorferi strains B31 and 2591.
  • OPTIMAL SPECIFICITY - Contains VIsE immunogenic lipoprotein.
  • CONVENIENT Kit includes ready to use controls for ease of use.
  • AUTOMATABLE Simple procedure is easy to automate.

GOLD STANDARD DIAGNOSTICS Immunoblot Confirmation 

  • NATIVE ANTIGEN STRUCTURE - The 3D (tertiary) antigen structure is maintained, unlike denatured Western blot proteins which only retain primary structure
  • lgG AND lgM IMMUNOBLOTS - Separate lgG and lgM immunoblot assays are available containing the CDC recommended specific antigens required for lmmunoblot interpretation.
  • ROBUST STRIPS - Strips are stabilized with a plastic backing and fixed in a booklet, making them easy to handle.
  • EASILY AUTOMATABLE - Strips are durable, easy to identify, automatable, with an incubation time of 30/30/10.
  • FAST AND SIMPLE PROCEDURE - Protocols include 1:100 serum dilution.
  • INTUITIVE RESULTS - Easy to read, precisely defined results, with internal test controls (serum and conjugate bands) and kit positive, negative, and cut off controls.

 

ORDERING INFORMATION - ELISA & IMMUNOBLOT ASSAYS

Product Order no. Format
Gold Standard Diagnostics Borrelia burgdorferi VlsE-OspC IgG/IgM ELISA Test Kit GSD01-1027 96 tests
Gold Standard Diagnostics Borrelia burgdorferi lgG/lgM ELISA Test Kit GSD01-1031 96 tests
Gold Standard Diagnostics Borrelia burgdorferi lgG ELISA Test Kit GSD01-1025 96 tests
Gold Standard Diagnostics Borrelia burgdorferi IgM ELISA Test Kit GSD01-1026 96 tests
Gold Standard Diagnostics Borrelia burgdorferi B31 IgG Line Blot Test Kit GSD01-1022 50 tests
Gold Standard Diagnostics Borrelia burgdorferi B31 IgM Line Blot Test Kit GSD01-1023 50 tests

Documents and brochures

MTTT Brochure
Total Lyme Solution