Mplex Monkeypox, Orthopox

Mplex Monkeypox, Orthopox (1 x 96 reactions) - PPOX6201

Real-time PCR assay designed for the simultaneous qualitative detection of the mpox virus and its differentiation from other orthopox viruses.

  • Dual-target multiplex assay: specific for MPXV (F3L) and generic for Orthopoxvirus genus (I7L)
  • RNase P gene is used as internal control
  • Fast and accurate results within 1 hour
  • Designed to aid investigations related to the prevalence and frequency of this virus
  • Evaluated by the Institute of Health Carlos III (ISCIII) in Spain – demonstrating 100% agreement to expected results when used on LightCycler® 480 Instrument II (Roche)
  • Validated by the French National Reference Center (CNR-LE) with the CFX Opus 96 (BioRad)
  • Validated for the AriaDx (Agilent Technologies) thermocycler
  • RUO

Disease: Mpox (formerly known as Monkeypox) 

Symptoms: The first symptoms of mpox include: a high temperature, a headache, muscle aches, backache, swollen glands, shivering (chills), exhaustion.
A rash usually appears 1 to 5 days after the first symptoms. The rash often begins on the face, then spreads to other parts of the body. This can include the genitals.The rash is sometimes confused with chickenpox. It starts as raised spots, which turn into small blisters filled with fluid. These blisters eventually form scabs which later fall off. The symptoms usually clear up in a few weeks.

Mechanism of Infection: Mpox can be caught from infected rodents (such as rats, mice and squirrels) in parts of west and central Africa. You can catch mpox from an infected animal if you're bitten or you touch its blood, body fluids, spots, blisters or scabs.It may also be possible to catch mpox by eating meat from an infected animal from central or west Africa that has not been cooked thoroughly, or by touching other products from infected animals (such as animal skin or fur). Mpox can also spread from person to person through:

  • touching clothing, bedding or towels used by someone with the mpox rash
  • touching mpox skin blisters or scabs (including during sex)
  • the coughs or sneezes of a person with the mpox rash
PPOX6201
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Mplex Monkeypox, Orthopox
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